p16 INK (16J3) Rabbit Monoclonal Antibody

p16 INK (16J3) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,FC,IP,IF-P

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CDKN2A
SKU: AMRe15577 Category: 兔单克隆抗体 Tags: , , , , , , , ,

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产品概述

产品名称(Product Name)

p16 INK (16J3) Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC-P,FC,IP,IF-P

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

CDKN2A

别名(Alternative Names)

CDKN2A; CDKN2; MTS1; isoforms 1/2/3; Cyclin-dependent kinase 4 inhibitor A; CDK4I; P16INK4; p16INK4a; Multiple tumor suppressor 1;

基因ID(Gene ID)

1029

蛋白ID(SwissProt ID)

P42771

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000, IHC-P/IF-P 1:100, FCM 1:200-1:500, IP 1:20

蛋白分子量(Molecular Weight)

17kDa

 

研究背景

p16-INK4A a cell-cycle regulatory protein that Interacts with CDK4 and CDK6, inhibiting their ability to interact with cyclins D. Inhibits the phosphorylation of the retinoblastoma protein by CDK4 or CDK6. Four alternatively spliced isoforms have been reported. Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.

 

研究领域


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