| 产品名称 |
Recombinant Human CXCR4 (N-Fc) |
| 英文名称 |
CXCR4/LAP-3/CD184 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human C-X-C Chemokine Receptor Type 4 is produced by our Mammalian expression system and the target gene encoding Met1-Ser46 is expressed with a human IgG1 Fc tag at the N-terminus. |
| Accession |
P61073 |
| 表达宿主 |
Human cells |
| 种属 |
Human |
| 预测分子量 |
30.6 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 50mM Tris-HCl, 100mM Glycine, pH7.5. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| CXCR4,CD184,Fusin,D2S201E,FB22,HM89,HSY3RR,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM |
| 背景介绍 |
| C-X-C chemokine receptor type 4 (CXCR4) is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. This receptor is one of several chemokine receptors that HIV isolates can use to infect CD4+ T cells./xa0CXCR4 stands out for its pleiotropic roles in both physiological and pathological conditions and it represents a crucial target in drug development. CXCL12 is the principal CXCR4 specific ligand and that the pro-inflammatory chemokine macrophage migration inhibitory factor (MIF) is also able to bind and activate CXCR4. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
