| 产品名称 |
Recombinant Mouse ST6GalNAc2 (C-6His) |
| 英文名称 |
ST6GALNAC2 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Mouse Alpha-N-acetylgalactosaminide Alpha-2,6-sialyltransferase 2 is produced by our Mammalian expression system and the target gene encoding Ser28-Arg373 is expressed with a 6His tag at the C-terminus. |
| Accession |
P70277 |
| 表达宿主 |
Human Cells |
| 种属 |
Mouse |
| 预测分子量 |
40.4 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 50mMTris-HCl, 150mM NaCl, pH 7.5. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Gal-beta-1,3-GalNAc alpha-2,6-sialyltransferase,GalNAc alpha-2,6-sialyltransferase II,ST6GalNAc II,Sialyltransferase 7B,SIAT7-B |
| 背景介绍 |
| Alpha‑N‑acetylgalactosaminide alpha ‑2,6‑sialyltransferase 2, is a type/xa0II membrane protein localized in the Golgi network and catalyzes 2,6‑sialylation of the Tn antigen. Sialyl‑Tn antigen is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis./xa0it has been reported that disregulation of this gene is involved in the pathogenesis of IgA nephropathy, a common kidney disease that occurs when antibody IgA accumulates in kidneys (4). The enzyme may also be used to synthesize a cancer vaccine. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
