| 产品名称 |
Recombinant Human PFKFB1 (C-6His) |
| 英文名称 |
PFKFB1/PFK/FBPase 1 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ser2-Tyr471 is expressed with a 6His tag at the C-terminus. |
| Accession |
P16118 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
55.6 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5%Trehalose, 1mM EDTA, 10% Glycerol, 0.1%Tween 80, pH7.8. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| 6-phosphofructo-2-kinase/fructose-2; 6-bisphosphatase 1; 6PF-2-K/Fru-2; 6-P2ase liver isozyme; Fructose-2; 6-bisphosphatase; PFKFB1; F6PK; PFRX |
| 背景介绍 |
| 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
