| 产品名称 |
Recombinant Human KLK3 (236AA, C-6His) |
| 英文名称 |
Kallikrein 3/PSA/KLK3 (25-261) |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Kallikrein-3/Prostate-specific Antigen is produced by our Mammalian expression system and the target gene encoding Ile25-Pro261 is expressed with a 6His tag at the C-terminus. |
| Accession |
P07288 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
27.1 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20 mM Glycine-HCl, 150 mM NaCl, 20% Glycerol, 10 mM CaCl2, 0.05% Tween 80, pH3.0. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤ -70℃, stable for 6 months after receipt.Store at ≤ -70℃, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Prostate-specific antigen; PSA; Gamma-seminoprotein; Kallikrein-3; P-30 antigen; Semenogelase; KLK3; APS |
| 背景介绍 |
| KLK3, also known as APS, is short for Prostate-specific antigen. It is a 261 aa. protein which belongs to the peptidase S1 family and Kallikrein subfamily. This protein has 5 isforms produced by alternative splicing. It is a secreted protein and can forms a heterodimer with SERPINA5 which can inhibit its activity. KLK3 is also strongly inhibited by Zn2+, 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins, which are avid zinc binders. KLK3 can hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
