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This gene encodes a protein that is involved in the Ras signal transduction pathway, growth inhibition, and nerve-growth factor induced differentiation processes, as determined in mouse and human cell line studies. In mouse, the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation. Multiple alternatively spliced transcript variants for this gene have been reported; one of these variants was found only in glioma tumors. [provided by RefSeq, Jul 2008],function:Potentially plays a role in the Ras signal transduction pathway. Capable of suppressing v-Ras transformation in vitro.,similarity:Contains 7 LRR (leucine-rich) repeats.,
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