| 产品名称 |
Recombinant Human DDR1 (C-Fc) |
| 英文名称 |
DDR1 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Epithelial discoidin domain-containing receptor 1 is produced by our Mammalian expression system and the target gene encoding Asp21-Thr416 is expressed with a human IgG1 Fc tag at the C-terminus. |
| Accession |
Q08345-1 |
| 表达宿主 |
Human cells |
| 种属 |
Human |
| 预测分子量 |
70.9 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 10% Trehalose, 100mM NaCl, 0.05% Tween 80, pH 7.8. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Epithelial discoidin domain-containing receptor 1; Epithelial discoidin domain receptor 1; CD167 antigen-like family member A; Cell adhesion kinase; Discoidin receptor tyrosine kinase; HGK2; CD167a; DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE |
| 背景介绍 |
| Discoidin domain receptor1 (DDR1) is a collagen activated receptor tyrosine kinase and an attractive anti-fibrotic target. Its expression is mainly limited to epithelial cells located in several organs including skin, kidney, liver and lung. DDR1 is a new potential target for drug discovery for human cancer and inflammatory disorders. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
