| 产品名称 |
Recombinant Human DLL3 (353-492, C-6His) |
| 英文名称 |
DLL3 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Delta-like protein 3 is produced by our Mammalian expression system and the target gene encoding Arg353-Leu492 is expressed with a 6His tag at C-terminus. |
| Accession |
Q9NYJ7 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
15.4 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 100mM NaCl, 8% Sucrose, 20% Glycerol, 0.05% Tween80, pH6.0. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening.Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Delta-like protein 3; Drosophila Delta homolog 3; Delta3; DLL3 |
| 背景介绍 |
| Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 is highly expressed in tumor cells and could be involved in the modification of tumor (immune) microenvironment. Neuroendocrine carcinomas are very aggressive tumors with few treatment options. DLL3 seems to be an optimal target for therapeutic intervention, as it is expressed mainly on the membrane of tumor cells with neuroendocrine origin. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
