| 产品名称 |
Recombinant SARS-CoV-2 NSP8 (C-6His) |
| 英文名称 |
NSP8 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
Please contact with the lab for this information |
| 蛋白构建 |
Recombinant 2019-nCoV NSP8 is produced by our E.coli expression system and the target gene encoding Ala1-Gln198 is expressed with a 6His tag at the C-terminus. |
| Accession |
YP_009725304.1 |
| 表达宿主 |
E.coli |
| 种属 |
SARS-CoV-2 |
| 预测分子量 |
25 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 8.5. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| SARS-CoV 2 nsp8 |
| 背景介绍 |
| Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
