| 产品名称 |
Recombinant Human CD200 R1 (C-Fc) |
| 英文名称 |
CD200 R1 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human CD200 Receptor 1 is produced by our Mammalian expression system and the target gene encoding Ala27-Leu266 is expressed with a human IgG1 Fc tag at the C-terminus. |
| Accession |
Q8TD46 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
53.9 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Cell Surface Glycoprotein CD200 Receptor 1; CD200 Cell Surface Glycoprotein Receptor; Cell Surface Glycoprotein OX2 Receptor 1; CD200R1; CD200R; CRTR2; MOX2R; OX2R |
| 背景介绍 |
| Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
