| 产品名称 |
Recombinant Human ASXL1 (N-GST) |
| 英文名称 |
ASXL1/Putative Polycomb group protein ASXL1/Additional sex combs-like protein 1/KIAA0978; |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Additional Sex Combs-Like Protein 1 is produced by our E.coli expression system and the target gene encoding Lys1477-Arg1541 is expressed with a GST tag at the N-terminus. |
| Accession |
Q8IXJ9 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
33.6 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Putative Polycomb group protein ASXL1; Additional sex combs-like protein 1; ASXL1; KIAA0978; |
| 背景介绍 |
| Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
