GMP Recombinant Human PDGF-BB-EnkiLife

GMP Recombinant Human PDGF-BB

规格：10μg 价格：￥900
规格：50μg 价格：￥3500
规格：100μg 价格：￥5800 SKU: PPH90037 Category: GMP细胞因子 Tags: Human, Unconjugated, Yeast

产品名称	GMP Recombinant Human PDGF-BB
蛋白名	PDGF-BB
纯度	Greater than 95% as determined by reducing SDS-PAGE
内毒素	≤10 EU/mg
蛋白构建	Recombinant Human PDGF-BB is produced by our Yeast expression system and the target gene encoding Ser82-Thr190 is expressed.
Accession #	P01127
蛋白标签	Tag free
表达宿主	Yeast
种属	Human
预测分子量	12.2 kDa
蛋白形态	Lyophilized
储存缓冲液	100mM Citrate sodium citrate, 5% Mannitol 0.1% Trehalose pH 6.5
运输方式	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
稳定性&储存	36 months at -20°C to -80°C in lyophilized state.6 months at -20°C to -80°C under sterile conditions after reconstitution.7-10 days at 2°C to 8°C under sterile conditions after reconstitution.Please minimize freeze-thaw cycles.
复溶	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

分子别名

PDGFBB; PDGF-BB

蛋白活性

The ED₅₀ for this effect is ≤10 ng/mL.

背景介绍

Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.