| 产品名称 |
Recombinant Human BCMA (C-Fc) |
| 英文名称 |
BCMA/TNFRSF17/CD269/B cell maturation antigen |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human B-cell Maturation Protein is produced by our Mammalian expression system and the target gene encoding Met1-Ala54 is expressed with a human IgG1 Fc tag at the C-terminus. |
| Accession |
Q02223 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
32.8 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Tumor necrosis factor receptor superfamily member 17;TNFRSF17;B-cell maturation protein;CD269 |
| 背景介绍 |
| B cell maturation protein (BCMA) is a type III membrane protein which belongs to the TNF receptor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
