| 产品名称 |
Recombinant Mouse IL-17RD (C-Fc) |
| 英文名称 |
IL-17RD/SEF |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Mouse Interleukin-17 receptor D is produced by our Mammalian expression system and the target gene encoding Cys17-Arg299 is expressed with a human IgG1 Fc tag at the C-terminus. |
| Accession |
Q8JZL1 |
| 表达宿主 |
Human Cells |
| 种属 |
Mouse |
| 预测分子量 |
58.7 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Interleukin-17 receptor D; IL-17 receptor D; IL-17RD; Interleukin-17 receptor-like protein; Il17rd; mSef; Il17rlm; Sef |
| 背景介绍 |
| The Il17rd gene encodes a transmembrane protein of the IL-17 receptor family. IL-17RD, originally termed similar expression to fibroblast growth factor (fgf) genes (Sef) as it belonged to the FGF synexpression group in zebrafish development, is the only orphan receptor without any known ligand within the IL-17R family. IL-17RD is a transmembrane protein shown to inhibit fibroblast growth factor signaling in developmental and cancer contexts, however its role as a tumor suppressor remains to be fully elucidated. The full-length IL-17 RD isoform is expressed in most adult tissues and during embryonic development. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
