| 产品名称 |
Recombinant Human IL-17RB (C-6His) |
| 英文名称 |
IL-17RB |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Interleukin-17 receptor B is produced by our Mammalian expression system and the target gene encoding Arg18/xadGly289 is expressed with a 6His tag at the C-terminus. |
| Accession |
Q9NRM6 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
30.7 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Interleukin-17 receptor B; IL-17RB; CRL4; EVI27; IL17BR |
| 背景介绍 |
| IL17RB(Interleukin-17 receptor B)is a receptor for the proinflammatory cytokines IL17B and IL17E. IL17RB is induced on human macrophages by IL4 and enhanced by TGFbeta.Human IL-17B R cDNA encodes a 502 amino acid (aa) residue type I membrane protein with a putative 17 aa signal peptide, a 275 aa extracellular domain, a 21 aa transmembrane domain and a 189 aa cytoplasmic tail.The protein Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines.Diseases associated with IL17RB include Chronic Mucocutaneous Candidiasis and Seborrheic Infantile Dermatitis.It’s reported that IL17RB expression might predict prognosis and benefit from gemcitabine in patients with resectable pancreatic cancer. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
