| 产品名称 |
Recombinant Human CD59 (C-6His) |
| 英文名称 |
CD59 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human CD59 Glycoprotein is produced by our Mammalian expression system and the target gene encoding Leu26-Asn102 is expressed with a 6His tag at the C-terminus. |
| Accession |
P13987 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
9.8 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| 1F5 antigen; 1F5; 20 kDa homologous restriction factor; CD59 antigen; CD59 glycoprotein; CD59; HRF20; HRF-20; MACIF; MAC-IP; MIC11; MIC11MSK21; MIN1; MIN2; MIN3; MIRL; p18-20; 16.3A5; EL32; FLJ38134; FLJ92039; G344 |
| 背景介绍 |
| CD59, also known as membrane attack complex inhibition factor (MACIF), Protectin, 1F5 antigen, HRF-20 and MIRL, is an approximately 20 kDa GPI anchored glycoprotein that is an important regulator of the complement system in blood. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
