| 产品名称 |
Recombinant Human VEGFB (N-Fc) |
| 英文名称 |
VEGFB/Vascular Eendothelial Growth Factor B |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Vascular Endothelial Growth Factor B is produced by our Mammalian expression system and the target gene encoding Pro22-Ala207 is expressed with a human IgG1 Fc tag at the N-terminus. |
| Accession |
P49765 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
45.7 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20 mM Glycine, 6% Sucrose, 5% Mannitol, 0.05% Tween80, pH3.0. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Vascular endothelial growth factor B;VEGF-B;VEGF-related factor;VRF |
| 背景介绍 |
| VEGFB, as known as VRF, is a member of the VEGF family of growth factors that share structural and functional similarity. By alternative splicing, two isoforms of mature VEGF-B containing 167 or 186 amino acid (aa) residues exist. VEGF-B is expressed in most tissues, especially in heart, skeletal muscle and pancreas. The two VEGF-B isoforms have identical amino-terminal cysteine-knot VEGF homology domains but the carboxyl end of VEGF-B167 differs from that of VEGF-B186 by the presence of a highly basic cysteine-rich heparin binding domain. VEGF-B167 and a proteolytically processed form of VEGF-B186 also bind neuropilin-1, a type I transmembrane receptor for semaphorins/collapsins, ligands involved in neuron guidance. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
