| 产品名称 |
Recombinant Human PLXDC1 (C-6His) |
| 英文名称 |
TEM7/PLXDC1 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Plexin Domain-Containing Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu19-Thr426 is expressed with a 6His tag at the C-terminus. |
| Accession |
AAH36059.1 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
46.53 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of PBS, 5% Threhalose, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Plexin Domain-Containing Protein 1; Tumor Endothelial Marker 3; Tumor Endothelial Marker 7; PLXDC1; TEM3; TEM7 |
| 背景介绍 |
| Plexin Domain-Containing Protein 1 (PLXDC1) is a single-pass type I membrane protein that belongs to the plexin family. Secreted PLXDC1 is localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells. PLXDC1 is expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. It can detect in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. PLXDC1 interacts with NID1 and may also interact with CTTN. It plays a important role in endothelial cell capillary morphogenesis, the proliferation and maintenance of neovascular endothelial cells in the formation of fibrovascular membranes (FVMs). |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
