| 产品名称 |
Recombinant Human MINPP1 (C-6His) |
| 英文名称 |
MINPP1/MIPP |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Multiple Inositol Polyphosphate Phosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Leu487 is expressed with a 6His tag at the C-terminus. |
| Accession |
Q9UNW1 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
53.14 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Multiple Inositol Polyphosphate Phosphatase 1; 2;3-Bisphosphoglycerate 3-Phosphatase; 2;3-BPG Phosphatase; Inositol (1;3;4;5)-Tetrakisphosphate 3-Phosphatase; Ins(1;3;4;5)P(4) 3-Phosphatase; MINPP1; MIPP |
| 背景介绍 |
| Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification). |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
