| 产品名称 |
Recombinant Human ECH1 (N-6His) |
| 英文名称 |
ECH1/Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase/mitochondrial |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, Mitochondrial is produced by our E.coli expression system and the target gene encoding Thr34-Leu328 is expressed with a 6His tag at the N-terminus. |
| Accession |
Q13011 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
34.5 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 8% Trehalose, 0.05% tween80, pH8.5. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤ -70℃, stable for 6 months after receipt.Store at ≤ -70℃, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Delta(3;5)-Delta(2;4)-dienoyl-CoA isomerase; mitochondrial; ECH1 |
| 背景介绍 |
| Human delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase(ECH1) is a member of the hydratase/isomerase superfamily and contains a C-terminal peroxisomal targeting sequence and localizes to peroxisomes. ECH1 shows high sequence similarity to enoyl-CoA hydratases of several species, particularly within a conserved domain characteristic of these proteins. The rat orthologlocalizes to the matrix of both the peroxisome and mitochondria.It can isomerize 3-trans, 5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. ECH1 plays an important role in the auxiliary step of the fatty acid beta-oxidation pathway. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
