| 产品名称 |
Recombinant Human PVR (C-6His) |
| 英文名称 |
CD155/PVR/Poliovirus Receptor/Nectin-Like Protein 5/NECL-5/PVS |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Poliovirus Receptor is produced by our Mammalian expression system and the target gene encoding Trp21-Asn343 is expressed with a 6His tag at the C-terminus. |
| Accession |
NP_006496 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
36.13 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Poliovirus Receptor; Nectin-Like Protein 5; NECL-5; CD155; PVR; PVS |
| 背景介绍 |
| Poliovirus Receptor (PVR) is a 70 kDa type I transmembrane single-span glycoprotein that belongs to the nectin-like (Necl) family and was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. PVR contains three Ig-like extracellular domains, a transmembrane segment, and a cytoplasmic tail. The normal cellular function of PVR maybe the involvement of intercellular adhension between epithelial cells. Alternate splicing of the PVR mRNA yields four different isoforms (α, β, γ, and δ) with identical extracellular domains. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
