产品概述
产品性能
免疫原
产品应用
研究背景
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation. [provided by RefSeq, Jul 2008],function:Can transform NIH 3T3 cells. Exhibits strong mitogenic and angiogenic properties.,similarity:Belongs to the heparin-binding growth factors family.,tissue specificity:Leukemia cell lines with platelet/ megakaryocytic differentiation potential.,
研究领域
MAPK_ERK_Growth;MAPK_G_Protein;Regulates Actin and Cytoskeleton;Pathways in cancer;Melanoma;
