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This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008],function:Might be involved in angiogenesis inhibition and suppression of glioblastoma.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 CUB domain.,similarity:Contains 1 GPS domain.,similarity:Contains 4 TSP type-1 domains.,tissue specificity:Strongly expressed in brain. Also detected in heart. Reduced expression is observed in some glioblastoma cell lines.,
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