产品概述
产品性能
免疫原
产品应用
研究背景
This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008],function:May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.,PTM:Myristoylation is required for tumor suppressor activity.,similarity:Belongs to the TUSC2 family.,tissue specificity:Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.,
研究领域
Cell Biology; Cell Cycle Cell Cycle Inhibitors; Epigenetics and Nuclear Signaling; Transcription; Cancer susceptibility; Tumor Suppressors; Transcription Factors; Cancer; Oncoproteins/suppressors