| 产品名称 |
Recombinant Human MOG (C-6His) |
| 英文名称 |
MOG/Myelin-oligodendrocyte glycoprotein |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Myelin Oligodendrocyte Glycoprotein is produced by our E.coli expression system and the target gene encoding Gly30-Gly154 is expressed with a 6His tag at the C-terminus. |
| Accession |
Q16653 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
15.2 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20 mM Glycine-HCl, 50 mM NaCl, 10% Trehalose, 0.05% Tween80, pH3.5. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Myelin-Oligodendrocyte Glycoprotein; MOG; MOG(1-125) |
| 背景介绍 |
| Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals, namely experimental autoimmune encephalomyelitis (EAE), in rodents and monkeys. |
注意事项
本司产品仅用于科研,不用于临床诊断和治疗