| 产品名称 |
Recombinant Human Serpin A3 (C-6His) |
| 英文名称 |
Serpin A3/AACT |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Serine Protease Inhibitor-clade A3 is produced by our Mammalian expression system and the target gene encoding His24-Ala423(Lys267Arg) is expressed with a 6His tag at the C-terminus. |
| Accession |
P01011 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
46.33 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, pH 7.5. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Alpha-1-Antichymotrypsin; ACT; Cell Growth-Inhibiting Gene 24/25 Protein; Serpin A3; SERPINA3; AACT |
| 背景介绍 |
| Serpin A3 belongs to the Serpin superfamily of serine protease inhibitors. Serpin A3 has been shown to inhibit some serine proteases, such as neutrophil cathepsin G and mast cell chymase. Serpin A3 is synthesized initially in the liver and secreted in plasma. Serpin A3 has been found in the amyloid plaques from the hippocampus of Alzheimer disease brains. In addition to, Serpin A3 is associated with liver disease and Parkinson disease and chronic obstructive pulmonary disease. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
