| 产品名称 |
Recombinant Human SENP7 |
| 英文名称 |
Sentrin-specific protease 7/SSP2/SENP7 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Sentrin-Specific Protease 7 is produced by our E.coli expression system and the target gene encoding Met695-Ala864 is expressed. |
| Accession |
Q9BQF6 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
19.8 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM HEPES, 5% Glycerol, pH 7.4. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Sentrin-Specific Protease 7; SUMO-1-Specific Protease 2; Sentrin/SUMO-Specific Protease SENP7; SENP7; KIAA1707; SSP2; SUSP2 |
| 背景介绍 |
| Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
