产品概述
产品性能
免疫原
产品应用
研究背景
This gene has been reported in PMID 9403053 as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11. [provided by RefSeq, Dec 2008],similarity:Contains 5 WD repeats.,
研究领域
Epigenetics and Nuclear Signaling; Transcription; Cancer susceptibility; Tumor Suppressors
