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This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009],function:Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.,PTM:Extensively processed by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues.,similarity:Belongs to the chromogranin/secretogranin protein family.,subcellular location:Neuroendocrine and endocrine secretory granules.,tissue specificity:Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver.,
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