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This gene consists of two exons and encodes a 104aa protein. Disruption of this gene by translocation t(2;3)(q33;q21) is associated with familial clear cell renal cancer. [provided by RefSeq, Sep 2010],disease:A chromosomal aberration involving DIRC1 is found in familial renal cell carcinoma 1-related translocation t(2;3)(q33;q21) (RCC1).,tissue specificity:Expressed at low steady-state level in adult placenta, testis, ovary, prostate, fetal kidney, spleen and skeletal muscle.,
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