CAPON Rabbit Monoclonal Antibody

CAPON Rabbit Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,ICC/IF,FC

种属(Reactivity):Human, Mouse, Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):NOS1AP
SKU: AMRe03909 Category: 兔单克隆抗体 Tags: , , , , , , , ,

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产品概述

产品名称(Product Name)

CAPON Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,ICC/IF,FC

种属反应性(Reactivity)

Human, Mouse, Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% protective protein.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

NOS1AP

别名(Alternative Names)

CAPON, KIAA0464,NOS1AP,Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein,C-terminal PDZ ligand of neuronal nitric oxide synthase protein,

基因ID(Gene ID)

9722

蛋白ID(SwissProt ID)

O75052

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,ICC/IF 1:50-1:200,FC 1:50-1:100

蛋白分子量(Molecular Weight)

Calculated MW:56 kDa;Observed MW: 56 kDa

 

研究背景

Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4 (By similarity). In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation (PubMed:33523862).

 

研究领域

Neuroscience


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