| 产品名称 |
Recombinant Human CTHRC1 (C-6His) |
| 英文名称 |
CTHRC1/Collagen triple helix repeat-containing protein 1 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Collagen Triple Helix Repeat-containing Protein 1 is produced by our Mammalian expression system and the target gene encoding Ser31-Lys243 is expressed with a 6His tag at the C-terminus. |
| Accession |
Q96CG8 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
24.1 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Collagen triple helix repeat-containing protein 1; Protein NMTC1; CTHRC1 |
| 背景介绍 |
| Collagen triple helix repeat-containing protein 1 is a protein that in humans is encoded by the CTHRC1 gene. It acts as a negative regulator of collagen matrix deposition. It may cause the disease of Barrett esophagus . Patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett esophagus is gastroesophageal reflux. The retrograde movement of acid and bile salts from the stomach into the esophagus causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
