| 产品名称 |
Recombinant Human ApoC2 (C-6His) |
| 英文名称 |
Apolipoprotein C-II/ApoC2 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Apolipoprotein C-II is produced by our E.coli expression system and the target gene encoding Thr23-Glu101 is expressed with a 6His tag at the C-terminus. |
| Accession |
AAP35354.1 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
10 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of PBS, 50% Glycerol, pH 7.4. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Apolipoprotein C-II; Apolipoprotein C2; APC2 and APOC2 |
| 背景介绍 |
| APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. |
注意事项
本司产品仅用于科研,不用于临床诊断和治疗