PURB Mouse Monoclonal Antibody

PURB Mouse Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB

种属(Reactivity):Human, Mouse
偶联物(Conjugate):Unconjugated
基因名(Gene Name):PURB
SKU: AMM86120 Category: 鼠单克隆抗体 Tags: , , , ,

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产品概述

产品名称(Product Name)

PURB Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB

种属反应性(Reactivity)

Human, Mouse

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

Mouse IgG1

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in PBS with 0.05% sodium azide.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

PURB

别名(Alternative Names)

Transcriptional activator protein Pur-beta, Purine-rich element-binding protein B, PURB

基因ID(Gene ID)

5814

蛋白ID(SwissProt ID)

Q96QR8

 

产品应用

稀释比(Dilution Ratio)

WB 1:2000-1:8000

蛋白分子量(Molecular Weight)

33.2kDa

 

研究背景

Has capacity to bind repeated elements in single- stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine- rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity).

 

研究领域


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