CYFIP1 Rabbit Monoclonal Antibody-EnkiLife

CYFIP1 Rabbit Monoclonal Antibody

规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB
种属（Reactivity）：Human,Mouse,Rat
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：CYFIP1 SKU: AMRe85477 Category: 兔单克隆抗体 Tags: Rabbit, Unconjugated, WB, Human, Mouse, Rat

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产品概述

产品名称（Product Name）	CYFIP1 Rabbit Monoclonal Antibody
描述（Description）	Recombinant rabbit monoclonal antibody
宿主（Host）	Rabbit
应用（Application）	WB
种属反应性（Reactivity）	Human,Mouse,Rat

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	CYFIP1
别名（Alternative Names）	SHYC; SRA1; SRA-1; P140SRA-1
基因ID（Gene ID）	23191
蛋白ID（SwissProt ID）	Q7L576

产品应用

稀释比（Dilution Ratio）	WB 1:500-1:1000
蛋白分子量（Molecular Weight）	Calculated MW: 145 kDa; Observed MW: 145 kDa

研究背景

Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA . Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes . May act as an invasion suppressor in cancers.

研究领域