Phospho-Phospholamban (Ser16) Rabbit Monoclonal Antibody

Phospho-Phospholamban (Ser16) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB

种属(Reactivity):Human,Mouse
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Phospho-Phospholamban (Ser16)
SKU: AMRe84873 Category: 兔单克隆抗体 Tags: , , , ,

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产品概述

产品名称(Product Name)

Phospho-Phospholamban (Ser16) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB

种属反应性(Reactivity)

Human,Mouse

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phosphorylated

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Phospho-Phospholamban (Ser16)

别名(Alternative Names)

PLN; PLB; Cardiac phospholamban; PLB

基因ID(Gene ID)

5350

蛋白ID(SwissProt ID)

P26678

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000

蛋白分子量(Molecular Weight)

Calculated MW: 6 kDa; Observed MW: 12,24 kDa

 

研究背景

Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca2+. Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.

 

研究领域


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