TIMP1 Rabbit Monoclonal Antibody

TIMP1 Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB

种属(Reactivity):Mouse
偶联物(Conjugate):Unconjugated
基因名(Gene Name):TIMP1
SKU: AMRe87792 Category: 兔单克隆抗体 Tags: , , ,

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产品概述

产品名称(Product Name)

TIMP1 Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB

种属反应性(Reactivity)

Mouse

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

TIMP1

别名(Alternative Names)

EPA; Clgi; Timp; TIMP-1; TPA-S1

基因ID(Gene ID)

21857

蛋白ID(SwissProt ID)

P12032

 

产品应用

稀释比(Dilution Ratio)

WB: 1:1000

蛋白分子量(Molecular Weight)

Calculated MW:23 kDa; Observed MW:26 kDa

 

研究背景

Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14 (By similarity). Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling.

 


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