GSDMD Rabbit Monoclonal Antibody

GSDMD Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB, IHC-P, FC, IP

种属(Reactivity):Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):GSDMD
SKU: AMRe87750 Category: 兔单克隆抗体 Tags: , , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

GSDMD Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB, IHC-P, FC, IP

种属反应性(Reactivity)

Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

GSDMD

别名(Alternative Names)

DF5L; M2-4; Dfna5l; GsdmD-1; Gsdmdc1; 1810036L03Rik

基因ID(Gene ID)

69146

蛋白ID(SwissProt ID)

Q9D8T2

 

产品应用

稀释比(Dilution Ratio)

WB: 1:1000 IHC-P: 1:200-1:1000 FC: 1:200-1:500 IP: 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW:53 kDa; Observed MW:53,31 kDa

 

研究背景

Enables phospholipid binding activity and wide pore channel activity. Involved in several processes, including defense response to bacterium; positive regulation of interleukin-1 beta production; and protein-containing complex assembly. Acts upstream of or within cellular response to extracellular stimulus. Located in cytosol; extracellular space; and plasma membrane. Part of NLRP3 inflammasome complex. Is expressed in several structures, including gut; liver; lung; metanephros; and spleen. Orthologous to human GSDMD (gasdermin D). [provided by Alliance of Genome Resources, Apr 2022]

 


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