Caspase-11 Rabbit Monoclonal Antibody-EnkiLife

Caspase-11 Rabbit Monoclonal Antibody

规格：20μL 价格：￥680
规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB, IP
种属（Reactivity）：Mouse
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：Caspase-11 SKU: AMRe86937 Category: 兔单克隆抗体 Tags: Rabbit, Unconjugated, WB, IP, Mouse

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产品概述

产品名称（Product Name）	Caspase-11 Rabbit Monoclonal Antibody
描述（Description）	Recombinant rabbit monoclonal antibody
宿主（Host）	Rabbit
应用（Application）	WB,IP
种属反应性（Reactivity）	Mouse

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt.
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	Caspase-11
别名（Alternative Names）	Caspl; ich-3; CASP-4; Casp11; CASP-11
基因ID（Gene ID）	12363
蛋白ID（SwissProt ID）	P70343

产品应用

稀释比（Dilution Ratio）	WB 1:500-1:2000,IP 1:50-1:100
蛋白分子量（Molecular Weight）	Calculated MW:43 kDa; Observed MW:43,38,25 kDa

研究背景

This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. [provided by RefSeq, Apr 2015]

研究领域