mSin3A Rabbit Monoclonal Antibody

mSin3A Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC,ICC,FC,IF

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):mSin3A
SKU: AMRe83980 Category: 兔单克隆抗体 Tags: , , , , , , , , ,

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产品概述

产品名称(Product Name)

mSin3A Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF,ICC,FC

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

mSin3A

别名(Alternative Names)

Histone deacetylase complex subunit Sin 3a; Paired amphipathic helix protein Sin 3a; SIN3 homolog A;;SIN3A

基因ID(Gene ID)

蛋白ID(SwissProt ID)

Q96ST3

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100

蛋白分子量(Molecular Weight)

Calculated MW: 145 kDa ; Observed MW: 150 kDa

 

研究背景

Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation.

 

研究领域


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