| 产品名称 |
Recombinant Human PDGF-BB |
| 英文名称 |
PDGF-BB |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<0.2 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Platelet-Derived Growth Factor BB is produced by our E.coli expression system and the target gene encoding Ser82-Thr190 is expressed. |
| Accession |
P01127 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
12.42 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc, pH 4.5. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| PDGFBB; PDGF-BB |
| 背景介绍 |
| Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
