| 产品名称 |
Recombinant Human IGF-I (67AA) |
| 英文名称 |
IGF-I |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<0.5 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Insulin-like Growth Factor I(4-70) is produced by our E.coli expression system and the target gene encoding Thr52-Ala118 is expressed. |
| Accession |
P05019 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
7.3 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc, pH 4.5 |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1 |
| 背景介绍 |
| Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone. |
注意事项
本司产品仅用于科研,不用于临床诊断和治疗