Notch 1 Rabbit Monoclonal Antibody

Notch 1 Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC,ICC,FC,IF

种属(Reactivity):Human,Mouse
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Notch 1
SKU: AMRe83723 Category: 兔单克隆抗体 Tags: , , , , , , , ,

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产品概述

产品名称(Product Name)

Notch 1 Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF,ICC,FC

种属反应性(Reactivity)

Human,Mouse

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in PBS with 0.05% sodium azide,0.05% protective protein and 50% glycerol.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Notch 1

别名(Alternative Names)

NOTC1, NOTCH1, TAN1, hN1, neurogenic locus notch homolog protein 1, neurogenic locus notch homolog protein 1 precursor,;Notch 1

基因ID(Gene ID)

蛋白ID(SwissProt ID)

P46531

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200,ICC 1:50-1:200,FC 1:20-1:100

蛋白分子量(Molecular Weight)

Calculated MW: 273 kDa ; Observed MW: 125 kDa

 

研究背景

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting.

 

研究领域


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