产品概述
产品性能
免疫原
产品应用
研究背景
Modulates negatively AKT-mediated GSK3B signaling.Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions.
研究领域