| 产品名称 |
Recombinant Human NPTN (C-6His) |
| 英文名称 |
Neuroplastin |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Neuroplastin is produced by our Mammalian expression system and the target gene encoding Gln29-His220 is expressed with a 6His tag at the C-terminus. |
| Accession |
Q9Y639 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
22.69 KDa |
| 制剂 |
Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2. |
| 运输方式 |
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| 分子别名 |
| Neuroplastin; Stromal Cell-Derived Receptor 1; SDR-1; NPTN; SDFR1; SDR1 |
| 背景介绍 |
| Neuroplastin (NPTN) is a 52-57 kDa member of the Ig-superfamily. Neuroplastin likely serves as a cell adhesion molecule, and is widely expressed in multiple tissues. Human Neuroplastin is 282 amino acids that contions two Ig-like domains and a 38 aa cytoplasmic region. Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. Neuroplastin may also regulate neurite outgrowth by activating the FGFR1 signaling pathway. It may play a role in synaptic plasticity. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
