| 产品名称 |
Recombinant Human PLA2G16 (N-6His) |
| 英文名称 |
PLA2G16/HRSL3 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Phospholipase A2 Group XVI is produced by our E.coli expression system and the target gene encoding Asp12-Asp132 is expressed with a 6His tag at the N-terminus. |
| Accession |
P53816 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
14-17 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 50mM NaCl, 1mM EDTA, pH8.0. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Group XVI Phospholipase A1/A2; Adipose-Specific Phospholipase A2; AdPLA; H-Rev 107 Protein Homolog; HRAS-Like Suppressor 1; HRAS-Like Suppressor 3; HRSL3; HREV107-1; HREV107-3; Renal Carcinoma Antigen NY-REN-65; PLA2G16; HRASLS3; HREV107 |
| 背景介绍 |
| Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models. |
注意事项
本司产品仅用于科研,不用于临床诊断和治疗