TRIM25 Rabbit Polyclonal Antibody

TRIM25 Rabbit Polyclonal Antibody

规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB,IHC-P,ICC/IF,FC,IP

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):TRIM25
SKU: APRab00268 Category: 兔多克隆抗体 Tags: , , , , , , , , , ,

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产品概述

产品名称(Product Name)

TRIM25 Rabbit Polyclonal Antibody

描述(Description)

Rabbit Polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC-P,ICC/IF,FC,IP

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

纯化方式(Purification)

Affinity Chromatography

 

免疫原

基因名(Gene Name)

TRIM25

别名(Alternative Names)

TRIM25; EFP; RNF147; ZNF147; E3 ubiquitin/ISG15 ligase TRIM25; Estrogen-responsive finger protein; RING finger protein 147; Tripartite motif-containing protein 25; Ubiquitin/ISG15-conjugating enzyme TRIM25; Zinc finger protein 147

基因ID(Gene ID)

7706

蛋白ID(SwissProt ID)

Q14258

 

产品应用

稀释比(Dilution Ratio)

WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200 IP: 1:20 FC: 1:50-1:100

蛋白分子量(Molecular Weight)

Calculated MW: 71 kDa; Observed MW: 71 kDa

 

研究背景

Functions as an ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection.

 

研究领域

Cell Biology


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