| 产品名称 |
Recombinant Human CSNK1G2 (N-6His) |
| 英文名称 |
Casein kinase I isoform gamma-2/CSNK1G2 |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Casein kinase I Isoform Gamma-2 is produced by our E.coli expression system and the target gene encoding Met1-Lys415 is expressed with a 6His tag at the N-terminus. |
| Accession |
P78368 |
| 表达宿主 |
E.coli |
| 种属 |
Human |
| 预测分子量 |
47.6 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 500mM NaCl, 10% Glycerol, 1mM DTT, pH 8.0. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Casein kinase I isoform gamma-2; CK1G2; CSNK1G2 |
| 背景介绍 |
| CSNK1G2 is a cytoplasmic protein which contains one protein kinase domain. It is amember of the CK1 Ser/Thr protein kinase family of the large casein kinase I (CKI) subfamily. CSNK1G2 participates in Wnt signaling, involves in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. It regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
