| 产品名称 |
Recombinant Human P4HB (C-6His) |
| 英文名称 |
Protein Disulfide Isomerase/P4HB/ERBA2L/PDI/PDIA1/PO4DB |
| 纯度 |
Greater than 95% as determined by reducing SDS-PAGE |
| 内毒素 |
<1 EU/µg as determined by LAL test. |
| 蛋白构建 |
Recombinant Human Prolyl 4-Hydroxylase Subunit Beta is produced by our Mammalian expression system and the target gene encoding Asp18-Lys505 is expressed with a 6His tag at the C-terminus. |
| Accession |
P07237 |
| 表达宿主 |
Human Cells |
| 种属 |
Human |
| 预测分子量 |
55.9 KDa |
| 制剂 |
Supplied as a 0.2 μm filtered solution of PBS, pH 7.4. |
| 运输方式 |
The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| 稳定性&储存 |
Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| 复溶 |
| 分子别名 |
| Protein Disulfide-Isomerase; PDI; Cellular Thyroid Hormone-Binding Protein; Prolyl 4-Hydroxylase Subunit Beta; p55; P4HB; ERBA2L; PDI; PDIA1; PO4DB |
| 背景介绍 |
| Protein Disulfide-Isomerase (P4HB) is an endoplasmic reticulum lumen protein that belongs to the protein disulfide isomerase family. P4HB contains two thioredoxin domains and catalyzes the formation, breakage, and rearrangement of -S-S- bonds in proteins. P4HB is involved in hydroxylation of prolyl residues in preprocollagen. P4HB has the ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner. P4HB plays a role in both the influx and efflux of S-nitrosothiol-bound nitric oxide. |
注意事项
本司产品仅用于科研，不用于临床诊断和治疗
