| 产品名称 | 
 Recombinant Human AREG  | 
| 英文名称 | 
 SDGF/Amphiregulin/AREG/AREGB/CRDGF/AR  | 
| 纯度 | 
 Greater than 95% as determined by reducing SDS-PAGE  | 
| 内毒素 | 
 <1 EU/µg as determined by LAL test.  | 
| 蛋白构建 | 
 Recombinant Human Amphiregulin is produced by our E.coli expression system and the target gene encoding Ser101-Lys198 is expressed.  | 
| Accession | 
 P15514  | 
| 表达宿主 | 
 E.coli  | 
| 种属 | 
 Human  | 
| 预测分子量 | 
 11.4 KDa  | 
| 制剂 | 
 Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.  | 
| 运输方式 | 
 The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.  | 
| 稳定性&储存 | 
 Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.Reconstituted protein solution can be stored at 2-8°C for 2-7 days.Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.  | 
| 复溶 | 
 Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.  | 
| 分子别名 | 
| Amphiregulin; AR; Colorectum Cell-Derived Growth Factor; CRDGF; AREG; SDGF; AREGB | 
| 背景介绍 | 
| Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy. | 
注意事项
本司产品仅用于科研,不用于临床诊断和治疗